U.S. vaccination supplies will fall sharply because of J&J factory problems.

WASHINGTON — Supplies of Johnson & Johnson’s one-dose coronavirus vaccine will be extremely limited until federal regulators approve production at a Baltimore manufacturing plant with a pattern of quality-control lapses, the White House’s pandemic response coordinator said on Friday.

With allocations of the company’s vaccine set to plunge by 86 percent next week, governors across the country warned that the loss of supplies they had been counting on would set back their vaccination drives.

Federal officials said Moderna and Pfizer-BioNTech, the other two federally authorized vaccine manufacturers, could make up some of the shortfall. They also pointed out that some states were not currently using all the vaccine allocated to them.

But increases from Moderna and Pfizer will not make up for the plunge in Johnson & Johnson supply. California will receive 400,000 fewer overall doses next week than this week, a drop of 15 percent, even with slight increases from Pfizer and Moderna. That will be followed by another 5 percent decrease the next week, state officials said on Friday. Officials in a broad band of states said the sudden drop in Johnson & Johnson supply would significantly slow inoculation efforts.

“The last thing we wanted to hear about was we’re getting less vaccines,” Gov. Larry Hogan of Maryland, a Republican, told reporters Friday. “We were hoping to ramp up as they’ve been promising.”

In a statement, Gov. Andrew M. Cuomo of New York, a Democrat, said, “We will not be able to get as many shots into New Yorkers’ arms as we would like.” He added, “As has been the case since the beginning of our vaccination effort, the X factor is supply, supply, supply.”

Some state health officials had hoped to use Johnson & Johnson’s one-shot, easily stored vaccine to target college students and other transient groups. Others were offering it at mass vaccination sites or directing it to rural areas.

Instead, shipment of doses of Johnson & Johnson next week will drop severely in states: California will fall from 572,700 to 67,600 doses, Texas from 392,100 to 46,300, Florida from 313,200 to 37,000 and Virginia from 253,400 to 27,900. ...